With the increasing longevity of the population worldwide, good appearance of aged skin is essential for a better quality of life of those people even in advanced age, with more independence and sometimes with intense professional and social activity. Scientific literature reports that some peptides that act as cellular messengers. These peptides are capable to initiate both collagen production and to regulate the enzyme collagenase involved in collagen degradation.

A variety of types of peptides are used in cosmetics. According to their mode of action, they have been classified into four main groups: signal peptides, carrier peptides, neurotransmitter peptides, and enzyme inhibitor peptides.

Signal peptides
Signal peptides show multiple actions, most especially stimulating the production of collagen, elastin, fibronectin, proteoglycan, and glycosaminoglycans. For example, palmitoyl pentapeptide-4 commercially known as Matrixyl, the most popular signal peptide, was discovered in 1999. It consists of lysine, threonine, lysine, and serine in the sequence and is demonstrated to stimulate the production of collagen I, III, and IV.
Carrier peptides
Carrier peptides were named based on their role in delivering trace elements like copper and magnesium to the skin. For a wound healing application, a peptide known as GHK-Cu was commercialized into a line of skin care products to keep the appearance of firmer and fuller.

Neurotransmitter peptides
Neurotransmitter peptides function by inhibiting acetylcholine release through a variety of chemical interactions. Acetyl hexapeptide-3, with trade name Argireline, is a neurotransmitter peptide functions topically to relax muscles by inhibiting vesicle docking through prevention of the SNARE complex formation. These neurotransmitter peptides have been shown to reduce certain types of wrinkles effectively.

Enzyme inhibitor peptides
Enzyme inhibitor peptides inhibit the efficiency of a key enzyme in some processes of metabolism. Many of the enzyme inhibitor peptides are extracted from botanical sources. Some peptides derived from rice proteins work well to retain more collagen, while certain soy-derived peptides can help prevent pigmentation.

To provide you with quality peptide products for the results you can trust…

As technology and research advance, cosmetic peptides are being used more and more all over the world. These cosmetic peptides are leading a beauty revolution with their multi-functional properties, including their ability to regulate certain biological functions. As the most thriving skin care companies pursue this booming field of research, there is the need, more than ever, to have high quality, custom cosmetic peptides. Bio-Synthesis has been helping companies break barriers by supplying the most trusted, reliable and affordable custom peptides for cosmetic companies. Using our state-of-the-art peptide synthesis facilities, Bio-Synthesis can manufacture single batch multi-gram research grade cosmetic peptides to fit your exact needs.

Please see our list of some of the most popular cosmetic peptides standing by. If you have a different cosmetic peptide synthesis requirement in mind, we can custom synthesize any peptide of any quantity or purity. All of these peptides play important role in cosmetic industry. Therefore the demand for high-quality cosmetic peptides has significantly increased. We at Lyotex are capable to provide a wide range of bioactive cosmetic peptides and also advisory services regarding cosmetic formulation. We will always endeavor to offer you the BEST QUALITY peptides. We can offer research- and GMP-grade cosmetic peptides according to your exact specifications. We also provide contract manufacturing services of cosmetic formulations with various base in creams, gels, lotions, butter, serums, etc. Please check our list of some of the most popular cosmetic peptides standing by. If you have a different cosmetic peptide synthesis requirement in mind, please let us know the peptide sequence, purity level required, and quantity needed. Our sales team will quickly generate a quote for you with price and delivery time.

Service Features

  • Quantity– mg to kg scale
  • Purity– Crude to >98%.
  • Modifications– We offer an extensive list of modifications options for your needs and can help you find the one that’s right for you.
  • Applicability – Peptides provided by Bio-Synthesis can be integrated into a wide range of applications.
  • Content – Our peptides come with Mass Spec Analysis, HPLC Profile and Certificate of Analysis. Additional content analysis, such as Amino Acid Analysis, is also offered.
  • Prices– Bio-Synthesis offers extremely competitive prices with large volume discounts. Please contact us for an official quote.

Quality Control:

Bio-Synthesis follows stringent guidelines to guarantee our cosmetic peptides surpass the highest of quality expectations. Each batch includes several analytical data sheets corresponding to the specific products.

PeptideCAS. NOSequence
AHK-Cu (Ala-His-Lys)2.Cu
Acetyl Hexapeptide 3616204-22-9Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
Acetyl tetrapeptide-15928007-64-1Tyr-Pro-Phe-Phe
Acetyl Tetrapeptide-2757942-88-4Ac-Lys-Asp-Val-Tyr
Acetyl Tetrapeptide-5820959-17-9Ac-Ala-His-Ser-His
Acetyl-Decapeptide-3 Ac-YRSRKYTSWY-NH2
Ac-KGHK-NH2 Ac-Lys-Gly-His-Lys-NH2
Decapeptide-12 H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH
Argireline (Acetyl-Hexapeptide-8)616204-22-9Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
Biotinoyl Tripeptide-1 (Biotin-GHK)299157-54-3Biotin-Gly-His-Lys
Copper peptide Gly-His-Lys.Cu
Copper Tripeptide-1 (GHK-Cu)89030-95-5(Gly-His-Lys).Cu
Copper Tripeptide-3 Ala-His-Lys.Cu
GHK Gly-His-Lys.HCl
Hexapeptide-12 Val-Gly-Val-Ala-Pro-Gly
Hexapeptide-2 (Nonapeptide-1) MP(dF)R(dW)FKPV-CONH2
HGG His-Gly-Gly
Human Oligopeptide-20124861-55-8Val-Gly-Val-Ala-Pro-Gly
Kyotorphin Tyr-Arg
Cysteine peptide Ac-RFAACAA-OH
Lysine peptide Ac-RFAAKAA-OH
Octapeptide-2 Thr – Ala – Glu – Glu – His – Glu – Val – Met – CONH2
PAL-Carnosine palmitoyl-Carnosine
PAL-GHK  (Palmitoyl-Oligopeptide)147732-56-7Palmitoyl-Gly-His-Lys
Palmitoyl-Tripeptide-3 Pal-AHK
PAL-KVK (Palmiotyl Tripeptide-5)623172-55-4Palmitoyl-Lys-Val-Lys-OH
Palmitoyl Hexapeptide171263-26-6Pal-Val-Gly-Val-Ala-Pro-Gly
Palmitoyl-Dipeptide-6 Pal-Lys-Val-Dab-OH
Pal-Lys-Val-Dab-Thr-OH Pal-Lys-Val-Dab-Thr-OH
Palmitoyl-TetraPeptide-7 Pal-GQPR
Palmitoyl-Tripeptide Pal-RFK
Pentapeptide-18 (Leuphasyl)64963-01-5Tyr-D-Ala-Gly-Phe-Leu
Pentapeptide-3 (Vialox)725232-44-0Gly-Pro-Arg-Pro-Ala-NH2
Peptide CK Arg-Lys-Arg
Peptide CK+ Ac-Arg-Lys-Arg-NH2
Peptide E Arg-Ser-Arg-Lys
rh-Oligopeptide-1  (Human EGF)62253-63-8Recombinant protein (53 amino acids)
RKR Arg-Lys-Arg
Snake tripeptide823202-99-9beta-Ala-Pro-Dab-NHBzl
Snap-8  (Acetyl-Octapetpide-8)868844-74-0Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2
Tripeptide-3 Ala-His-Lys.HCl